5 Best Pet Ear & Eye Care Medications - Sept. 2026

BEST OF THE BEST

Zymox

Otic Pet Ear Treatment with Hydrocortisone

Effective & Gentle

A gentle treatment for numerous types of persistent ear problems in dogs and cats that's made with natural enzymes.

Check Price Check Price

PROS

Treats recurrent ear infections caused by fungal, yeast, and bacterial infections with a trio of enzymatic ingredients.
Made with a low dose of hydrocortisone that soothes symptoms and inflammation until issues are resolved.
Well-tolerated by most cats and dogs with few side effects.

CONS

Severe infections may require a stronger treatment, but most pet owners who have used it rave about its effectiveness.

BEST BANG FOR THE BUCK

Vetericyn

Antimicrobial Ophthalmic Gel for Pets

Soothes Irritated Eyes

This soothing gel keeps eyes moisturized, and acts as a preventative against inflammation and infection. Can ease pet's urge to paw at their eyes by calming discomfort.

Check Price Check Price

PROS

Benefits eyes by increasing moisture, which could help prevent irritation and infection.
Doesn't contain harsh ingredients or antibiotics.
A good choice for cats and dogs that are prone to watery, red, inflamed eyes.
Can be used for horses too.

CONS

Gel-like consistency makes it challenging to apply to some cats' eyes.
Won't work for established infections.

Miracle Care

R-7M Ear Mite Treatment for Dogs & Cats

Treats Ear Mites

Liquid medication that treats parasitic ear infections, especially mites that can result in scratching and discomfort if left untreated.

Check Price Check Price

PROS

Formulated with pyrethrin that targets and treats ear mites, a parasite that causes pets to scratch and leads to irritation.
Calms symptoms that come with infestations.
Also helps control ticks.
Doesn't have an offensive odor.

CONS

May not work on major infestations that have led to secondary ear infections.
May sting for a few seconds when placed in the ears.

Neo-Poly-Bac (Generic)

Ophthalmic Ointment for Dogs & Cats

Treats Eye Infections

An effective treatment for pet eye infections that is tolerated well by most dogs and cats. Makes most pets' eyes feel better as it fights infections.

Check Price at Chewy.com View at Chewy.com

PROS

Formulated with neomycin, Polymyxin, and bacitracin to treat numerous types of eye infections in dogs and cats.
Soothes irritation and calms swelling.
Ointment is easy to use.

CONS

Rare incidence of allergic reactions noted.
May sting slightly, but this sensation tends to fade fairly quickly for most pets.

Animax

Ointment for Dogs & Cats

For the Ears and Skin

A Neomycin-based treatment that works well for various skin and ear issues. If you need an antibiotic for ear infections in your cat or dog, this ointment works well and is easy to administer.

Check Price at Skimlinks View at Skimlinks

PROS

An ointment form of an antibiotic that is prescribed to treat severe or persistent ear infections.
May also be used to treat canine infections of the anal glands and some inflammatory skin conditions.

CONS

Made with a steroid ingredient that could cause side effects in sensitive animals, including excessive urination.
Not recommended for long-term use.

Why trust BestReviews?

BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews

BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.About BestReviews

How We Tested

We recommend these products based on an intensive research process that's designed to cut through the noise and find the top products in this space. Guided by experts, we spend hours looking into the factors that matter, to bring you these selections.

Click here for testing insights

First Reviewed

November 09, 2021

Models
considered

Hours
researched

Written by Jennifer Manfrin

Updated August 2025

Most dogs and cats experience various ear and eye health conditions throughout their lives. Infections, irritations, and parasitic infestations are unfortunately common problems that can cause pets to experience discomfort along with the urge to scratch the affected area, which can often make these problems worse. The good news is that there are several effective medications that alleviate symptoms and promote healing. If your furry friend is experiencing a problem with his ears or eyes, it’s important to check with your vet first to rule out serious disease and get a recommendation or prescription for the most effective treatment. Many medications that treat ear and eye conditions can be conveniently purchased from a reputable online retailer.

Best Pet Ear & Eye Care Medications

Pros and Cons

Pros and Cons

Pros and Cons

Pros and Cons

Pros and Cons

Shop Similar Products Get the best products related to our top picks