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Best supplements to boost your metabolism for 2026

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Get a jump-start on a healthy new year

If you're looking to support your health goals heading into the new year, metabolism supplements may be able to help. Metabolism — the process by which your body converts food into energy — is influenced by many factors, from age to muscle mass, genetics, activity level and overall health. Supplements can support various aspects of metabolic health and energy production at the cellular level, but they don't magically "boost" metabolism in the dramatic way advertisements sometimes suggest. The reality is more nuanced: Certain ingredients support the body's natural energy production processes, cardiovascular health and cellular function that contribute to overall metabolic wellness.

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The supplements people turn to for metabolic support typically fall into categories: those supporting cellular energy production (like CoQ10), those promoting cardiovascular health and blood flow (like beet root supplements) and those supporting organs involved in metabolism (like liver support formulas). Some people also consider gut health supplements, since emerging research connects digestive wellness to metabolic function. These aren't substitutes for the fundamentals — regular exercise, adequate sleep, proper nutrition and stress management — but some people use them as complementary tools alongside healthy lifestyle habits.

Before starting any supplement regimen, consult with health care providers, especially if you have existing health conditions or take medications. And note that supplements aren't regulated like pharmaceuticals, so quality and transparency matter when choosing brands.

Shop this article: 1MD Nutrition CoQ10 - for Heart Health & Cellular Energy Production, 1MD Nutrition CardioFitMD, 1MD Nutrition LiverMD - Liver Support Supplement

Here are supplements from 1MD Nutrition that many customers on Amazon choose to support different aspects of their metabolic and overall health — and you can, too, as you head into 2026.

These supplements can give you a healthy start to 2026

1MD Nutrition CoQ10 - for Heart Health & Cellular Energy Production

This CoQ10 supplement supports heart health and cellular energy production. Coenzyme Q10 is a compound the body produces naturally that plays a role in cellular energy generation. Levels of it may decrease with age. This supplement's formula aims to support cardiovascular wellness and energy at the cellular level.

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1MD Nutrition CardioFitMD

This beet root powder supplement supports nitric oxide production for cardiovascular health. Beets naturally contain nitrates that the body converts to nitric oxide, which supports healthy blood flow. The formula is vegan and keto-friendly to support both plant-based and low-carb diets — plus it has a high fiber content to support digestive health.

1MD Nutrition LiverMD - Liver Support Supplement

This liver support supplement contains Siliphos milk thistle extract and NAC. The liver plays a central role in metabolism by processing nutrients and filtering blood, and milk thistle has been traditionally used for liver support. NAC serves as a precursor to glutathione, an antioxidant the body produces. This formula aims to support healthy energy levels and overall wellness.

1MD Nutrition GutMD - L-Glutamine Capsules w/Prebiotic for Gut Health

This gut health supplement features L-glutamine with prebiotics. L-glutamine is an amino acid that supports the integrity of the intestinal lining, while prebiotics nourish beneficial gut bacteria. Emerging research suggests connections between gut health and metabolic function.

Prices listed reflect time and date of publication and are subject to change.

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